abstract |
The invention relates to novel carboxylic acids and isosteres of heterocyclic ring compounds of the formula which have multiple heteroatoms within the heterocyclic ring to new derivatives containing N-linked diketo, sulfonamides, ureas and carbamates attached thereto, to their preparation and use for treatment of neurological diseases, including physically impaired nerves and neurodegenerative diseases, as well as for the treatment of alopecia and for the promotion of hair growth. In the formula A, X, Y, Z, D and n have the meanings given in the description. |