http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-103852-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 1999-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53adc9d9b2221ff3d129b009616d1bb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96a84f6eb44fcc6493732c2dad9019df |
publicationDate | 2000-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BG-103852-A |
titleOfInvention | COS-2 SELECTIVE CARPROPHENE FOR TREATMENT OF DISEASE AND INFLUENCE IN DOGS |
abstract | The invention relates to the treatment or prophylaxis of inflammatory processes and diseases in dogs associated with the activity of induced cyclooxygenase-2 (CGG-2). Reduced or eliminable side effects caused by the simultaneous inhibition of the activity of the constitutive cyclooxygenase-1 (CGG-1) by selective inhibition of the CGG-2 activity with respect to CGG-1 activity are reduced or eliminated. The ratio of selectivity or CGG-2: CGG-1 inhibition activity is at least 3: 1 based on ex vivo inhibition levels measured in whole blood. The inhibitor is selected from the group of anti-inflammatory compounds consisting essentially of salicylic acid derivatives, paramiphenol, indole and indene acetic acids, heteroarylacetic acids, arylpropionic acids, anthranilic acids, enolic acids and alkanones. The inhibitor particularly consists of (+) (S) -enantiomeric 6-chloro-methyl-9H-carbazole-2-acetic acid. |
priorityDate | 1997-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.