http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-102662-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate | 1998-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db9de4320f76723f21c14a7a18d0d4eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd9d78d1ae76bc5511f9684061924f68 |
| publicationDate | 2000-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-102662-A |
| titleOfInvention | METHOD FOR OBTAINING A PORPHYREN PHOTOSENSIBILIZER FOR DIAGNOSIS AND CERA THERAPY |
| abstract | The product obtained by this method is used in medicine for the diagnosis and treatment of cancer as well as for the treatment of some non-malignant diseases. The method is simple, inexpensive and effective, with reproducible content of the individual components and especially the precursors of the active antitumor fraction. The synthesis is carried out under conditions where maximum conversion of the starting hematoporphyrin to the desired photosensitizer derivatives takes place using minimal amounts of acidic mixture, eliminating the intermediate filtration, and the neutralization of the reaction mixture is also achieved with minimal amounts of sodium acetate. The resulting product is removed by vacuum filtration for a short time and without loss and the necessary neutral pH is achieved using minimal amounts of phosphate buffered sodium chloride solution. The lyophilized porphyrin product was basified with a subsequent reduction in the pH of the medium to 7.0-7.5 and equilibrated with 0.9% aqueous sodium chloride solution or Ringer's standard solution. |
| priorityDate | 1998-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.