| abstract |
The compounds find use as antiviral agents, especially against retroviruses, and as anti-inflammatory and anti-sclerotic agents. The isothiazolones have the general formula wherein A is a mono- or bicyclic ring which may contain up to three heteroatoms from the group of O, S and N, R1 and R2 are substituents such as alkyl, alkoxy, hydroxy, nitro, cyano, amino and carboxy groups and R5 is alkyl, cycloalkyl, phenyl and het. |