| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9fb65ced8ed42eb9f7254b7d9337a58 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-724 |
| filingDate |
1996-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e8c0581ef4ac21e60999da1b3965993
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6df9a1d81775ca7256f67c445500921a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a7494f47de0431ea0617e79a352ffc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b49174724b3a94abd268289f8a4a805
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cadb262db2712d20e3e720398332f179 |
| publicationDate |
1996-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BG-100313-A |
| titleOfInvention |
COMPOSITIONS INCLUDING N-MORPHOLINO-N-NITROSOMAINACETONETRYL AND CYCLODEXTRIN |
| abstract |
The new complexes are stable in the solid state and are formed from N-morpholino-N-nitrosoaminoacetonitrile (SIN-1A) and cyclodextrin or cyclodextrin derivatives, optionally containing ions as a catalyst or stabilizer. The complexes release nitrous oxide at room temperature when dissolved in water or water systems. Preferably the ions are anions of carboxylic and / or inorganic acids and / or alkali and / or ammonium cations. The invention also relates to pharmaceutical compositions and kits containing these complexes. The kits can be used as NO separation standards, with NO being released in a predetermined amount and speed at dissolution in an aqueous medium. The complexes are prepared by subjecting 3-morpholinoisondinimine (SIN-1) at a suitable pH of the catalytic activity of ions for displacement of equilibrium to SIN-1A formation in the presence of cyclodextrin or derivatives thereof capable of being incorporated into a complex. The formed SIN-1A immediately binds to a complex, optionally containing ions. The components are mixed or ground whole or oxygen-free aqueous solutions containing these components are lyophilized and then re-dried under vacuum |
| priorityDate |
1994-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |