| abstract |
Compounds of the formula wherein m is 0, 1 or 2; notes 2 to 5; x is a carbonyl or a group of the formula wherein R5 is n or alkyl; y is an alkylene chain optionally substituted by one or more alkyl groups containing from 1 to 3 carbon atoms; z is an alkylene chain containing from 2 to 5 carbon atoms optionally substituted by one or more alkyl groups; r is phenyl substituted with one or more halogen substituents or naphthyl; r1 and r2 which are the same or different are n, alkyl or arylalkyl, with the proviso that when r1 is benzyl, R2 is methyl or their pharmaceutically acceptable salts. The compounds are administered in the treatment of depression, anxiety neurosis, parkinson's disease, general obesity, cognitive impairment, seizures, neurological diseases, epilepsy and as neuroprotective agents. |