http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BE-904458-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1576a87a56e0b26ef425cf917fc094ff |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 |
filingDate | 1986-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19215676085896372593abdee22c1f47 |
publicationDate | 1986-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BE-904458-A |
titleOfInvention | NOVEL PROCESS FOR THE PREPARATION OF (D-TRP6) -LHRH AND BENZHYDRYLAMINIC RESIN AND PEPTIDE COMPLEX. |
abstract | Process for the preparation of (D-Trp6) -LHRH in solid phase on a benzhydrylaminic resin, characterized in that the protected amino acids are introduced onto the polymer support with double condensation, in that the hydroxyl radical of the serine is protected thanks to a benzyl group, the hydroxyl radical of tyrosine thanks to a 2,6-dichlorobenzyl group, the guanidine group of arginine thanks to a tosyl group, the indole nucleus of L- and D-tryptophan thanks to a formyl group and l nitrogen-TT of the imidazolic nucleus of histidine thanks to a benzyloxymethyl group, and in that the final removal of the protection of the side chains and the separation of the peptide from the support are carried out thanks to a treatment subsequent to the hydrofluoric acid at low and high concentration. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1343808-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7122628-B2 |
priorityDate | 1985-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.