| abstract |
New 4-substituted androst-4-ene-3,17-dione derivatives of formula I in which R is an optionally substituted amino group or azido, one of the residues R1 and R2 is hydrogen and the other is hydrogen or an alkyl, alkenyl or alkynyl group, and (x) and (y) are each independently a single or double bond. Applications: steroid-aromatase inhibitor drugs useful for the treatment of hormone-dependent tumors. |