| abstract |
The invention relates to lyophilized pharmaceutical formulations comprising plasma proteins or their derivatives, hyaluronic acid or a derivative thereof, and optionally one or more other pharmaceutically active ingredients, such as clonidine or a derivative thereof. , wherein the lyophilized pharmaceutical formulations are characterized by a reconstitution time of less than 15 minutes. The invention further relates to methods of preparing such formulations and their use for the treatment of musculoskeletal diseases such as bone or joint disease. |