| abstract |
The substituted benzamides of formula described in the figure where the various symbols have meanings such that these compounds are, for example 4-amino-N- (1-azabicyclo [2.2.2] oct-3-yl) -5-chloro -2-hydroxybenzamide, 4-amino-N (1-azabicyclo [2.2.2] oct-3-yl) -2- (butan-2-on-3-yl) -oxy-5-chlorobezamide, 2- allyloxy-4-amino-N- (1-azabicyclof [2.2.2] oct-3-yl) -5-chlorobenzamide or 4-amino-N- (1-azabicyclo [2.2.2] oct-3-yl) -5-chloro-2-propargyloxybenzamide are antiemetics. |