| abstract |
It has been discovered that quinolines of low molecular weight, for example ergolines, exhibit immunosuppressive properties. These quinolines are particularly suitable for the preparation of pharmaceutical compositions suitable for co-administration with another immunosuppressive agent, in order to reduce the side effects caused by the other immunosuppressive agent. Preference is given to a quinoline chosen from (5R, 8S, 10R) -2,6-dimethyl-8 -pivaloylamino-ergoline, lisuride, pergoline, terguride, proterguride, 2-bromerguride, metergoline, dosergoside, FCE 21336 and GYKI 32887. |