| abstract |
New intermediates of formula where R1 is a hydrogen atom or lower alkyl radical, and R is a radical -CH = O, -CH = [(OY), (OY)], -CH = (0-0), - CH2- (OH) or -CH2 (X) where X is a conventional leaving radical and Y is a lower alkyl radical, used to prepare certain histamine H2 receptor antagonists. These antagonists are particularly suitable for the treatment of peptic ulcer. |