| abstract |
The disclosure features novel lipids and compositions involving the same. Nanoparticle ncompositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, nand PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as nRNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, nfor example, regulate polypeptide, protein, or gene expression. n19000930_1 (GHMatters) P111932.AU.1 |