abstract |
The present invention relates to methods for predicting peptides or polypeptides such as T cell nepitopes useful for immunotherapy such as for vaccination. In particular, the present invention nrelates to methods for predicting whether peptides or polypeptides such as tumor-associated nantigens or epitopes, in particular tumor-associated neoantigens or neoepitopes, are nimmunogenic and, in particular, useful for immunotherapy such as for vaccination. The nmethods of the invention may be used, in particular, for the provision of vaccines which are nspecific for a patient's tumor and, thus, in the context of personalized cancer vaccines. |