abstract |
The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)n5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable saltthereof, and in n5 particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5na]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal nto 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising nthe same, their use as a medicament and in methods of treatment of diseases and disorders in nhumans including women of child bearing potential and pediatric patients in which aldosterone n0 over-exposure contributes to the deleterious effects of said diseases or disorders, as well as nprocesses for preparing said inventive compounds. n11255763_1 (GHMatters) P111063.AU |