abstract |
METHODS AND PRODUCTS FOR NUCLEIC ACID PRODUCTION AND nDELIVERY nABSTRACT nThe present invention relates in part to nucleic acids, including nucleic acids encoding nproteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic nacids to cells, tissues, organs, and patients, methods for inducing cells to express proteins nusing nucleic acids, methods, kits and devices for transfecting, gene editing, and nreprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these nmethods, kits, and devices. Methods and products for altering the DNA sequence of a cell are ndescribed, as are methods and products for inducing cells to express proteins using synthetic nRNA molecules, including cells present in vivo. Therapeutics comprising nucleic acids nencoding gene-editing proteins are also described. |