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filingDate 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2021282414-A1
titleOfInvention Systems And Methods For Determining Microsatellite Instability
abstract Presented herein are techniques for determining microsatellite instability. The techniques ninclude generating a reference sample dataset representative of or mimicing a hypothetical nmatched sample for an individual sample of interest. The reference sample dataset may be ngenerated from a set of reference normal samples that are not matched to the sample of ninterest. For samples of interest lacking a matched sample, the reference sample dataset may nbe used to determine microsatellite instability and to provide an indication of a presence, nabsence, or degree of microsatellite instability of the sample of interest. The reference sample ndataset may be generated such that individual microsatellite regions associated with a high ndegree of variability between ethnic groups are filtered out, masked, or otherwise not nconsidered.
priorityDate 2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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