| abstract |
A system and method for isolating and analyzing single cells, wherein the system includes: an array of wells ndefined at a substrate, each well including an open surface and a well cavity configured to capture cells in none of a single-cell format and single-cluster format, and a fluid delivery module including a fluid reservoir nsuperior to the array of wells through which fluid flow is controlled along a fluid path in a direction parallel nto the broad face of the substrate; and wherein the method includes: distributing a population of cells and na population of non-cell particles across the array of wells through the fluid reservoir to increase capture nefficiency of individual cell-particle pairs within the array of wells, and processing the captured cell-particle npairs at the set of wells. |