| abstract |
In the present invention structural modification of terpenoids are performed and evaluation of nbiological activities of natural terpenoids and their semisynthetic derivatives is evaluated. We ndecided to perform some structural modifications in the natural diterpenes, various nitrogen ncontaining heterocyclic compounds such as pyrazolines, pyridazinones and pyrrolones have been nstudied extensively for the development of pharmaceutically important antimicrobial agents.The ninvention discloses novel lupeol derivatives, having anti tubercular activity, which can be, a npotential agent for the therapy of TB. |