Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6012ce2ccf64fbc34ba201c9f11ada92 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-162 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
filingDate |
2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae7d5956d30fcd8306dbf8030ef64f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47ab56c4bc9adb0c998e11bae29d7f36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba681f4d91b948c5ca4940425fcd4120 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7625c43c0b346db9a3ee861456e50f32 |
publicationDate |
2020-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2020267278-A1 |
titleOfInvention |
Trimer stabilizing HIV envelope protein mutations |
abstract |
Human immunodeficiency virus (HIV) envelope proteins having mutations that stabilize nthe trimeric form of the envelope protein are provided. The HIV envelope proteins have certain namino acid substitutions at specified positions in the envelope protein sequence. The HIV nenvelope proteins described herein have an improved percentage of trimer formation and/or an nimproved trimer yield as compared to an HIV envelope protein that does not have one or more of nthe indicated amino acid substitutions. Also provided are nucleic acid molecules and vectors nencoding the HIV envelope proteins, as well as compositions containing the HIV envelope nproteins, nucleic acid, and vectors. |
priorityDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |