| abstract |
BENZOXABOROLECOMPOUNDSANDUSESTHEREOF nABSTRACT nCompounds whose structure comprises Formula 1l, nR1 nt2 n0 O nB n5 X NH2 nFormula II nor a compound whose structure comprises Formula III nR1 OH nR2 nOH nB n\0 nX NH2 nFormula III n10 wherein X is selected from chloro, fluoro, bromo and iodo, R 1 and R 2 are each nindependently selected from H, -CH 3, -CH 2CH 3 , -CH 2CH2CH 3, or -CH(CH 3)2,; ncompositions containing them, their use in therapy, including their use as antinmycobacterial agents, for example in the treatment of a mycobacterial infection in a nmammal, and methods for the preparation of such compounds, are provided. n15 |