| abstract |
Compounds having a structure of Formula 1: or a pharmaceutically acceptable salt, tautomer or nstereoisomer thereof, wherein RR 2, R 3, RR, R, R1C, Rld x, nn 2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen nreceptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of nsubjects in need thereof, including prostate cancer are also provided. |