| abstract |
Methods for decreasing mucus elasticity or viscosity, in a subject in need thereof, comprising nadministering an effective amount of a thiosaccharide mucolytic agent, and compounds and npharmaceutical compositions useful for the methods. The thiosaccharide mucolytic agent ncomprises at least one tetrahydropyrane ring substituted with at least one thiol-containing nmoiety or at least one thioacetyl moiety.nWO 2014/153009 PCT/US2014/028656 n5/6 nFIG. 6 n150 nC 100nU) n50. n0 n0n0 2 4 6 8 10 12 nTime (min) |