http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2020102560-A4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e58e36f7a13a808b80b0ebfeb0b4d0dc |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2020-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9b64a14889497f1db006ba64a6a86a5 |
publicationDate | 2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2020102560-A4 |
titleOfInvention | Phosphate derivatives and use thereof |
abstract | The present invention discloses a compound with the following formula (I), or a tautomer, mesomer, nracemate, enantiomer, and diastereoisomer thereof, or a mixture form thereof, or a pharmaceutically nacceptable salt thereof, or a prodrug molecule thereof, wherein D is selected from: nIl5 R566 12R R 12 nA R90 F' R F R R90 R12 nR8 7 R 7 R 8 n6 R78 n nR n6 The ninvention further discloses the use of the compound in the preparation of drugs for preventing nand/or treating cancers, and the use of the compound in the preparation of drugs for inhibiting ncancer metastasis. The compound of the present invention can effectively inhibit the proliferation nand metastasis of cancer cells by adjusting the acidity of a tumor microenvironment to achieve a nbetter effect in clinical cancer treatment, and has broad application prospects. nR 2 RinK-Z Y-L--(C)n1 nE-D n2)n n- ~ n3 |
priorityDate | 2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.