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filingDate 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82a4df40f58a77a05ebaea69cbf74623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_987343007387d130aea06d6bd00168c6
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publicationDate 2022-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2019288048-B2
titleOfInvention Combined medicine comprising gemcitabine-encapsulated liposome composition and immune checkpoint blockade
abstract The present invention addresses the problem of providing a medicine prepared by combining a liposome composition with an immune checkpoint blockade, wherein gemcitabine is encapsulated in a dissolved state in liposomes in the liposome composition. According to the present invention, a medicine which is a combination of (A) a liposome composition with (B) an immune checkpoint blockade is provided, wherein the liposome composition comprises liposomes each having an inner aqueous phase and an aqueous solution constituting an outer aqueous phase and having the liposomes dispersed therein, gemcitabine is encapsulated in a dissolved state in the liposomes, and the liposome composition and the immune checkpoint blockade are administered simultaneously or sequentially.
priorityDate 2018-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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