abstract |
C:\Interwoen\NRPortbl\DCC\RBR\19490239_l.doex-31/10/2019 nABSTRACT nCompounds having a structure of Structure I: nR5 R6 nR N nR3 ,y2 nR2 ' NRn1 n5 nor a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, R2 , R3 , nR4, R6, Y' and Y2 are as defined herein, and wherein at least one of R3 or R4 is a straightnchain CI-C6 haloalkyl, are provided. Uses of such compounds for treatment of various nindications, including prostate cancer, as well as methods of treatment involving such n10 compounds are also provided. |