abstract |
Kv1.3 potassium channel antagonists nAbstract nThe present invention relates to compounds which are capable of selectively binding to and ninhibiting the activity of the potassium channel Kv1.3. The invention also relates to n5 pharmaceutical compositions comprising such compounds and to the use of said compounds and nsaid pharmaceutical compositions for the treatment or prevention of autoimmune diseases, nobesity, parodontitis and/or tissue transplant rejection. |