http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2019213320-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5801589d3ca582e9d1f998f3fec65d08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
filingDate | 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56c3b18cf9ed5bf6b12a8ea2ec24ece9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889bccce70e035c84dd3cf099862849a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ca6e3fd19590b1c84bf07fcfa5800c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f9a22a752f1945ff33a1ceda393e1a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb6a0a599049c07da2312f6b97db0f67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13493ddccf3e58aa527fc82b602ea2b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0615e76a3893b0be93bff59355e42d6b |
publicationDate | 2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2019213320-A1 |
titleOfInvention | Systems and methods for ex-vivo organ care using lactate as an indicator |
abstract | The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions. The present application describes a method for using lactate measurement in the arterial and the venous blood lines of an organ care system heart perfusion device to evaluate 1) the overall perfusion status of an isolated heart, 2) the metabolic status of an isolated heart and 3) the overall vascular patency of an isolated donor heart. This aspect of the present invention uses the property of myocardial cell's unique ability to produce/generate lactate when they are starved of oxygen and to metabolize/utilize lactate for energy production when they are well perfused with oxygen. fT CD - ~ T .- r', 12 |
priorityDate | 2007-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 348.