| abstract |
Disclosed are an mTOR inhibitor, a pharmaceutical composition and the use thereof. The mTOR inhibitor includes one of kelimycin, isovalerylspiramycin I, isovalerylspiramycin II and isovalerylspiramycin III, or a combination of two or three of isovalerylspiramycin I, isovalerylspiramycin II and isovalerylspiramycin III. The pharmaceutical composition thereof can also comprise a drug for treating and/or preventing diseases associated with an mTOR pathway as the second active ingredient. The mTOR inhibitor has an obvious inhibitory effect on cells having diseases associated with an mTOR pathway, and is used for preparing drugs for treating and/or preventing diseases associated with the mTOR pathway. |