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filingDate 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2019205010-A1
titleOfInvention Multiplex biomarker for use in evaluation of state of accumulation of amyloid B in brain, and analysis method for said evaluation
abstract Provided are a biomarker for evaluating a cerebral AP accumulation state using amyloid precursor protein (APP)-derived 5 AP and Af-like peptides in a living body-derived sample as an index, and a method for analysis thereof. A marker for determining a cerebral A accumulation state, the marker comprising a combination of at least two ratios selected from the group consisting of: a ratio of A$l-39 (SEQ ID NO.: 1) level to Al-42 (SEQ ID NO.: 3) level: 0 Afl-39/Al-42; a ratio of Al-40 (SEQ ID NO.: 2) level to Afl-42 (SEQ ID NO.: 3) level: Afl-40/Af-42; and a ratio of APP669-711 (SEQ ID NO.: 4) level to Al-42 (SEQ ID NO.: 3) level: APP669-711/Al-42, in a living body-derived sample. 11482311_1 (GHMatters) P108121.AU.1
priorityDate 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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