| abstract |
The present invention relates to compound (I) x W, - - U Rn V R'n' R" z N Y T 5 wherein: z means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a -CN group, a hydroxyl group, a -COOR group, a (Ci-C3)fluoroalkyl group, a (Ci-C3)fluoroalkoxy group, a -NO2 group, a -NRiR 2 group, a (C-C4)alkoxy group, a 10 phenoxy group and a (C1-C3)alkyl group, said alkyl being optionally mono-substituted by a hydroxyl group, n is 1, 2 or 3, n' is 1 or 2, R' is a hydrogen atom, a halogen atom or a group chosen among a (C1-C3)alkyl group,, a hydroxyl group, a -COOR 1 group, a -NO 2 group, a -NRiR 2 group, a morpholinyl 15 or a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalkyl group, a (Ci-C 4)alkoxy group and a -CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating cancer. Some of said compounds are new and also form part of the invention. |