abstract |
SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1-[4-(PYRIDIN-2-YLOXY)nCYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,IOB-TETRAAZAnBENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF nAbstract n0, N nN4 nThe present invention provides processes to manufacture substituted 1-[4n(Pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,I0b-tetraaza-benzo[e]azulenes. nAlso disclosed are compounds useful as intermediates in the methods of the invention. |