abstract |
The present invention provides heteroaryl substituted pyrrolo[2,3 b]pyridines (1) and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. {Y)rim(Z / A ' R H(I |