| abstract |
The present invention comprises compounds of Formula (1). wherein: X, A1 , A2, A3, A4, R1 , R2 , and R3 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORyt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1. |