Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86bd6bf5a2cb8ba68b45b2c4a13e6b14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32784d1ba4f017e1fe91badd81d9ebaf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-465 |
filingDate |
2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a42e1586dd0dce7bde2ab77d592f3af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_227d08794ce651b03b963d5f25c8ab62 |
publicationDate |
2020-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2018391657-A1 |
titleOfInvention |
Enantiomeric separation of racemic nicotine by addition of an O,O'-disubstituted tartaric acid enantiomer |
abstract |
The present invention relates to a method of separating racemic nicotine of Formula (l-a) as a mixture of the (R)- and (S)-enantiomers into the enantiomerically pure (S)- and (R)-nicotine represented by Formula (l-b) and (l-c), by adding a mixture of the L- and the D-enantiomer of a O,O'-disubstituted tartaric acid, wherein the molar ratio of the L- to the D-enantiomer is from 80:20 to 95:5, and obtaining the (S)-nicotine of formula (l-b), or by adding O,O'-dibenzoyl-D-tartaric acid and obtaining the (R)-nicotine of formula (l-c). |
priorityDate |
2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |