| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d4dc8f7db08607c344fa0afbad4f8e3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab83b35a43cd34c8d3a96b97f4148a3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_282bcf8f94b38e53f7da899a094aa62c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95ec5c0dbea24599dac5e9838c830f5e |
| publicationDate |
2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2018377716-A1 |
| titleOfInvention |
Nucleic acid, composition and conjugate containing same, and preparation method and use |
| abstract |
Provided are a siRNA for suppressing hepatitis B virus gene expression, and a pharmaceutical composition and conjugate containing the siRNA. Each nucleotide in the siRNA is an independent modified nucleotide. The siRNA contains a positive-sense strand and an antisense strand. The positive-sense strand of the siRNA contains a nucleotide sequence 1 having an equal length to a nucleotide sequence shown in SEQ ID NO: 155 with no more than three nucleotide differences, and the antisense strand of the siRNA contains a nucleotide sequence 2 having an equal length to a nucleotide sequence shown in SEQ ID NO: 156 with no more than three nucleotide differences. |
| priorityDate |
2017-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |