| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9852aeac9e264dec85886e291702522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90dc31127e33e0ae677059b9fad7c961 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14152
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14151 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761 |
| filingDate |
2018-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_242dc5ef9cc4287b3734f57aa6da3b65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec1c8d3753a500c5171da8b9050a4331 |
| publicationDate |
2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2018265414-A1 |
| titleOfInvention |
Methods and compositions for modifying assembly-activating protein (APP)-dependence of viruses |
| abstract |
This disclosure describes and demonstrates the utility of a particular sequence motif within an Adeno-associated virus (AAV) capsid protein that enables the assembly-activating protein (AAP)-dependence of the AAV to be modified. Thus, this sequence motif can be use to address and alleviate at least one of the bottlenecks encountered in the production of virus vectors. In particular, this disclosure describes a minimal motif defined through a novel phenotype-to-phylogeny mapping method that can be used to modify the AAP dependence of a virus. |
| priorityDate |
2017-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |