Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_077209f9cfeac17d8a084da546a6c532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9ab700e3fd932b7ccc18d8ea4ec29dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_910ef5c85e4bf91537ee87d95b0c7418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ac6d88176ca78153f908b2112f3af5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cda24a652f0649c1486eab7998f81c71 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 |
filingDate |
2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8e9c3b691d0ae6a7d5be50b5d3e938 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6023f3940f241d8e8e48dc5bb1c0e4e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5a65e01e884eded054691c9acea3fe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03a356a4582345106e960ac2378bfbb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4654e13edafc35b6e617ff20c69fbc96 |
publicationDate |
2019-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2018215905-A1 |
titleOfInvention |
Idoxuridine and its analogs as neuroprotectans for the treatment of parkinsonism |
abstract |
The invention relates to compounds that are useful in the treatment of parkinsonism, such as parkinsonism in connection with Parkinson's disease (PD); dementia with Lewy bodies (DLB); multiple system atrophy (MSA); corticobasal degeneration (CBD); or progressive supranuclear palsy (PSP). The said compounds include in particular idoxuridineand analogs thereofas well as their metabolic precursors, such as ropidoxuridine.The invention further relates to method for identifying compounds useful for the treatment of parkinsonism, said methods comprising detecting the capability of compound to increase the amount of GPR37 in cell membranes.The invention further relates to methods for the chemical synthesis of ropidoxuridine. |
priorityDate |
2017-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |