Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3438811768d5b0caa638b0c8f6c17a92 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 |
filingDate |
2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ef354a013526ab790217f7216293281 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffb21a7bb14bc67bafc60101f4215d32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_099fe3faa466a60a5a17c0236068fec1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdcc55b7d5cc33926c95000f3de7715f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd4d82cf1a59a09ab9fa74a800e50502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_268d1085d92457c008b2d85858f3539c |
publicationDate |
2020-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2018202782-B2 |
titleOfInvention |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
abstract |
This invention provides, and in certain specific but non-limiting aspects relates to: n- assays that can be used to predict whether a given ISV will be subject to protein ninterference as described herein and/or give rise to an (aspecific) signal in such an assay n(such as for example in an ADA immunoassay). Such predictive assays could for example nbe used to test whether a given ISV could have a tendency to give rise to such protein ninterference and/or such a signal; to select ISV's that are not or less prone to such protein ninterference or to giving such a signal; as an assay or test that can be used to test whether n10 certain modification(s) to an ISV will (fully or partially) reduce its tendency to give rise nto such interference or such a signal; and/or as an assay or test that can be used to guide nmodification or improvement of an ISV so as to reduce its tendency to give rise to such nprotein interference or signal; n- methods for modifying and/or improving ISV's to as to remove or reduce their tendency nto give rise to such protein interference or such a signal; n- modifications that can be introduced into an ISV that remove or reduce its tendency to ngive rise to such protein interference or such a signal; n- ISV's that have been specifically selected (for example, using the assay(s) described nherein) to have no or low(er)/reduced tendency to give rise to such protein interference or n20 such a signal; n- modified and/or improved ISV's that have no or a low(er)/reduced tendency to give rise nto such protein interference or such a signal. |
priorityDate |
2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |