abstract |
The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially ndifferentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a npluripotent or multipotent state. In further embodiments the invention also relates to nreprogrammed somatic cells produced by methods of the invention, to uses of said cells, and nto methods for identifying agents useful for reprogramming somatic cells. |