| abstract |
Provided are a new microtubule protein inhibitor and applications therefor, said microtubule protein inhibitor being a series of compounds based on substituted heterocyclic skeletons, having as targets the colchicine binding sites of tubulin. The structure is as below: formula (1), wherein for formula (A), n independently expresses an integer between 0 and 5, the condition being that n≤5, A represents mono- or poly-substituted groups, said groups being selected among H, C |