abstract |
The present invention provides new and improved methods for screening for and/or identifying T cell epitopes, as well as various assays and compositions (such as nucleic acid molecules, vectors, viruses, peptides, libraries, and cells), that are useful in carrying out such methods. Such methods and compositions can be used to predict and/or study the toxicity and off-target effects of T-cells, TCRs, or TCR-like molecules. |