| abstract |
Disclosed in the present invention are deuterated 3-(4,5-substituted pyrimidinamine) phenyl derivatives and applications thereof. The deuterated 3-(4,5-substituted pyrimidinamine) phenyl derivatives are compounds of a structure of formula (I) or pharmacologically acceptable salts thereof. The compounds or the salts thereof can be used for treating or preventing diseases or states of illnesses by means of certain mutant forms of epidermal growth factor receptors (EGFRs), can effectively inhibit the growth of multiple kinds of tumor cells, have an inhibiting effect on other proteases of the EGFRs and Her families, and can be used in the preparation of antitumor drugs. |