| abstract |
Directed bioadhesion coatings, methods of forming directed bioadhesion coatings, and methods of directing bioadhesion are provided. In particular, methods of forming directed bioadhesion coatings include providing a substrate having a graft monomer layer on a surface thereof, selectively removing discrete portions of the graft monomer layer to expose the substrate surface, polymerizing any remaining portions of the graft monomer layer via reversible addition-fragmentation chain-transfer (RAFT) polymerization with a RAFT chain transfer agent to form a plurality of graft polymers, and simultaneously with polymerizing the remaining graft monomer layer, grafting the plurality of graft polymers to the substrate to form a chemical pattern on the substrate. |