| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035 |
| filingDate |
2017-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3060077eeaac65b08f01c30433ae8cd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6cfce19994b8e9b9f8211afcca3c0d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5fc441e1e113309bb4282c083cae1be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adc2a9fef889b9adccb699bee7c450c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6832c60e3d6a154aff7d1e5940cb34d4 |
| publicationDate |
2021-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2017254713-C1 |
| titleOfInvention |
Bifunctional molecules for degradation of EGFR and methods of use |
| abstract |
The present application provides bifunctional compounds of Formula (I): Targeting Ligand which act as protein degradation inducing moieties for EGFR and/or a mutant thereof. The present application also describes methods for the targeted degradation of EGFR and/or a mutant thereof through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to EGFR and/or a mutant thereof which can be utilized in the treatment of disorders modulated by EGFR or a mutant thereof. |
| priorityDate |
2016-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |