| abstract |
Abstract: The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A XX 7EID XiiLPNL X 1 6Xi 7XiQW X2 1AFIX25 X26LX28D, and ii) an amino acid sequence which has at least 86 % identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatments. C:\poi\word\SPEC-1098927.docx |