http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2017219032-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98cb1b197f761c87cd3caf32bc247e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ade0fe9455a0a34ebd8a98d9cef29ecb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d168184dafec3206f8f0422d0235e19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e89669a4d2795e78df7634e2fc8745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a471e75447860a6e313c46de5f817b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd970be5a8caccc91604740948f1160d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73362c1c95a8dc1b320b01d26b04c2d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a60807ad1b9d63e44c89dadcb7949782 |
| publicationDate | 2018-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2017219032-B2 |
| titleOfInvention | Novel tetrahydropyridopyrimidine compound or salt thereof |
| abstract | A method of treating a disease selected from the group consisting of ovarian cancer, bladder cancer, uterine cancer, pancreatic cancer, and hepatocellular cancer, comprising administering an effective amount of a tetrahydropyridopyrimidine compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof to a subject in need thereof: N'--N N' x (1) wherein, in the formula, X represents a halogen atom or a halogeno-C1 _3 alkyl group; R represents a C6_14 aryl group which is substituted with R' and may be substituted simultaneously with R 2, or a 5- or 6 membered heteroaryl group which is substituted with R' and may be substituted simultaneously with R2 ; R represents a hydrogen atom, a phenyl group, a hydroxy-C1 alkyl group, a hydroxy-C3 7 cycloalkyl group, a Ci-6 alkoxy group which may be substituted with Ra, a C3-7 cycloalkylaminosulfonyl group, a 3- to 7-membered monocyclic heterocycloalkylsulfonyl group, a halogeno-C1 _3 alkoxycarbonylamino group, a halogeno-C1 _3 alkylcarbonylamino group, a 3- to 7-membered monocyclic heterocycloalkanecarbonyl group substituted with a hydroxy-Ci 6 alkyl group, or -(CH 2)n C(=0)-NHRf; R2 represents a hydrogen atom, a halogen atom, or a halogeno Ci_3 alkyl group; Ra represents a Ci-6 alkylpyrazolyl group, a triazolyl group, a tetrazolyl group, or a Ci-6 alkylsulfonylpiperazinyl group; Rf represents a halogeno-C 1 _3 alkyl group, a hydroxy-C1 - alkyl group, a hydroxy-C3_7 cycloalkyl group, a hydroxy-C 3_7 cycloalkyl-C1 _6 alkyl group, or a CI_ alkyl group substituted with Rfa; Rfa represents a C1-6 alkylpyrazolyl group, a halogeno-C1 _3 alkylthiazolyl group, an oxadiazolyl group, or a halogeno-C1 _3 alkyloxadiazolyl group; and n represents an integer of from 0 to 3. |
| priorityDate | 2014-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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