http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2017201214-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_006e91eddabe95ad7aa889123d31cb9a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
| filingDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8b66348d6a6a070f9d59a88f16dc11f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccec9352d29b5d77d16a26320335df6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea7e68d6c26746716ce71dcbb9b1582c |
| publicationDate | 2019-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2017201214-B2 |
| titleOfInvention | Conjugation methods |
| abstract | CONJUGATION METHODS Abstract This invention describes a method of conjugating a cell binding agent such as an antibody with an effector group (e.g., a cytotoxic agent) or a reporter group (e.g., a radionuclide), whereby the reporter or effector group is first reacted with a bi-functional linker and the mixture is then used without purification for the conjugation reaction with the cell binding agent. The method described in this invention is advantageous for preparation of stably-linked conjugates of cell binding agents, such as antibodies with effector or reporter groups. This conjugation method provides in high yields conjugates of high purity and homogeneity that are without inter-chain cross-linking and inactivated linker residues. |
| priorityDate | 2009-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1314.