| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b8e2017b321a8b2a55f4c091d6b89c0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-16 |
| filingDate |
2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6cde014c141aeafc6a426b8a1e65f9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d89a21c7167bbe3bb69d8ed046a26d90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a79e855d808142a7a73a0b875e947f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53ee274e173a7364424406a3a379c09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49e0cb44c7d4eeea8a37b4d82e9d67c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8963a0ee111b331467a23de43458eb5 |
| publicationDate |
2018-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2016359420-A1 |
| titleOfInvention |
An improved process for the preparation of sugammadex and its intermediates |
| abstract |
The present application provides an improved process for the preparation of sugammadex which comprises the halogenation of γ-cyclodextrin in a suitable organic solvent to give 6-per-deoxy-6-per-halo-γ-cyclodextrin, wherein halo is bromo or chloro, reacting the halogenated γ-cyclodextrin with 3- mercaptopropionic acid in the presence of alkoxide base to obtain sugammadex of formula I. This application also provides isolation of 6-per-deoxy-6-per-chloro-γ- cyclodextrin as a crystalline compound and its use for the preparation of sugammadex of formula (I). |
| priorityDate |
2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |