Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_902474a26ba632dd12fead50cee4fa7f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-664 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-2429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 |
filingDate |
2016-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_532207dc8aaa6781230f89693b5d3ac0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec974b786d463ac706f511387889eec9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d02efe8a63bcd5eea56ed0c4c6f6d80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1e0b760e201b3b566bd564ed1cd970a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca02c88df8d9c51b9e53f8269044b252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e9b0fd42e2f1f3679e5c22c707604ee |
publicationDate |
2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2016357728-A1 |
titleOfInvention |
(R)- and (S)-1-(3-(3-N,N-dimethylaminocarbonyl)phenoxyl-4-nitrophenyl)-1-ethyl-N,N'-bis (ethylene)phosphoramidate, compositions and methods for their use and preparation |
abstract |
Provided herein are optically active compounds of the formulae (ii); and (III) and pharmaceutical compositions thereof. Also provided herein are processes of making these compounds and resolving the racemic mixture or the enrichment of same with in one of its enantiomers to provide (R)- and (S)-1-(3-(3-N,N-dimethylaminocarbonyl)phenoxyl-4-nitrophenyl)-1-ethyl-N,N'-bis(ethylene)phosphoramidate, and methods of treating cancer comprising administering such compounds. |
priorityDate |
2015-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |